{"id":18373,"date":"2024-06-06T10:20:58","date_gmt":"2024-06-06T02:20:58","guid":{"rendered":"https:\/\/www.nikyang.com\/?p=18373"},"modified":"2024-06-06T10:24:30","modified_gmt":"2024-06-06T02:24:30","slug":"usp4-pvt","status":"publish","type":"post","link":"https:\/\/www.nikyang.com\/news\/usp4-pvt\/","title":{"rendered":"\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u6027\u80fd\u9a8c\u8bc1\uff08PVT\uff09\u6700\u65b0\u52a8\u6001"},"content":{"rendered":"\n<p>\u5173\u6ce8\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u6027\u80fd\u9a8c\u8bc1\u7684\u5c0f\u4f19\u4f34\u8d76\u7d27\u8fc7\u6765\u56f4\u89c2\uff01\u5728\u300aDissolution Technology\u300b\u5168\u65b0\u4e00\u671f\u671f\u520a\u4e2d\uff0c\u520a\u5370\u4e86\u4e00\u7bc7\u9898\u4e3a\u201cApplication of Salicylic Acid Tablets in the Performance Verification Test for the Flow-Through Cell Apparatus\u201d\uff08\u6c34\u6768\u9178\u6821\u6b63\u7247\u5728\u6d41\u6c60\u6cd5\u4eea\u5668\u6027\u80fd\u9a8c\u8bc1\u4e2d\u7684\u5e94\u7528\uff09\u7684\u6587\u7ae0\uff0c\u8fd9\u5bf9\u4e8e\u56fd\u5185\u4f7f\u7528\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u7684\u4e1a\u754c\u540c\u4ec1\u6765\u8bf4\u65e0\u7591\u662f\u4e00\u4e2a\u632f\u594b\u4eba\u5fc3\u7684\u597d\u6d88\u606f\u3002\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u5982\u4f55\u6267\u884c\u6027\u80fd\u9a8c\u8bc1\u4e00\u76f4\u662f\u4e1a\u754c\u70ed\u95e8\u63a2\u8ba8\u7684\u8bdd\u9898\uff0c\u56fd\u9645\u56fd\u5185\u5747\u65e0\u53ef\u53c2\u8003\u6807\u51c6\u3002\u8be5\u6587\u7ae0\u7684\u53d1\u8868\uff0c\u4e3a\u4e1a\u754c\u6307\u5f15\u4e86\u53ef\u53c2\u8003\u7684\u65b9\u5411\u3002<a href=\"https:\/\/dissolutiontech.com\/issues\/202405\/DT202405_A02.pdf\">\u70b9\u51fb\u6d4f\u89c8\u8be5\u5b8c\u6574\u6587\u7ae0<\/a>\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3><span class=\"has-inline-color has-vivid-cyan-blue-color\"><strong>\u6587\u7ae0\u6458\u8981\uff1a<\/strong><\/span><\/h3>\n\n\n\n<p>\u6d41\u901a\u6c60\u6cd5\u662f\u8fdb\u884c\u7f13\u63a7\u91ca\u5236\u5242\u3001\u96be\u6eb6\u6027\u836f\u7269\u548c\u8bf8\u591a\u7279\u6b8a\u5242\u578b\uff08\u5982\u6df7\u60ac\u5242\u3001\u8f6f\u80f6\u56ca\u3001\u690d\u5165\u7269\u3001\u5fae\u7403\u548c\u8102\u8d28\u4f53\uff09\u6eb6\u51fa\u5ea6\u6d4b\u8bd5\u7684\u4f18\u9009\u88c5\u7f6e\u3002\u5c3d\u7ba1\u591a\u5e74\u4ee5\u524d\u836f\u5178\u6536\u8f7d\u4e86\u6d41\u6c60\u6cd5\u8bbe\u5907\uff0c\u4f46\u6ca1\u6709\u5b98\u65b9\u7684\u6027\u80fd\u9a8c\u8bc1\u6d4b\u8bd5\uff08PVT\uff09\u65b9\u6cd5\u3002\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u6c34\u6768\u9178\u7247\u88ab\u7528\u4e8e\u5f00\u53d1\u6d41\u6c60\u6cd5\u7684 PVT \u65b9\u6cd5\u3002\u4e0e\u8f6c\u7bee\u6cd5\u548c\u6868\u6cd5\u6eb6\u8680\u548c\u96f6\u7ea7\u91ca\u653e\u673a\u5236\u76f8\u4f3c\uff0c\u6c34\u6768\u9178\u7247\u88ab\u8bc1\u660e\u662f\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u88c5\u7f6e PVT \u7684\u4e00\u4e2a\u826f\u597d\u7684\u6f5c\u5728\u53c2\u8003\u6807\u51c6\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>\u5728\u5b9e\u9a8c\u9636\u6bb5 I \u4e2d\uff0c\u91c7\u7528\u5b9e\u9a8c\u8bbe\u8ba1\u6cd5\uff08DoE\uff09\u7cfb\u7edf\u7814\u7a76\u4e86\u56db\u4e2a\u53c2\u6570\u5bf9\u6c34\u6768\u9178\u6eb6\u51fa\u5ea6\u7684\u5f71\u54cd\u3002\u5176\u4e2d\uff0c\u7247\u5242\u52a0\u8f7d\u65b9\u5f0f\u662f\u5f71\u54cd\u6eb6\u51fa\u5ea6\u7684\u6700\u91cd\u8981\u53c2\u6570\uff1b\u6d41\u901f\u548c\u6d41\u901a\u6c60\u5185\u5f84\uff08ID\uff09\u4e5f\u6709\u663e\u8457\u5f71\u54cd\uff1b\u800c\u6e29\u5ea6\u5bf9\u6eb6\u51fa\u7684\u5f71\u54cd\u53ef\u4ee5\u5ffd\u7565\u4e0d\u8ba1\u3002\u5728\u9636\u6bb5 II \u4e2d\uff0c\u4e24\u4e2a\u6d4b\u8bd5\u5b9e\u9a8c\u5ba4\u7684\u56db\u4e2a\u4e0d\u540c\u5206\u6790\u5458\u5728\u4e0d\u540c\u7684\u6d41\u901a\u6c60\u8bbe\u5907\uff08\u5373\u56db\u540d\u5408\u4f5c\u8005\uff09\u8fdb\u884c\u4e86\u91cd\u590d\u6027\u548c\u518d\u73b0\u6027\u8bc4\u4f30\uff0c\u5e76\u786e\u5b9a PVT \u7684\u521d\u6b65\u9a8c\u6536\u6807\u51c6\u3002\u7b2c&nbsp;II&nbsp;\u9636\u6bb5\u7684\u5b9e\u9a8c\u6761\u4ef6\u662f\u5c06\u7247\u5242\u653e\u7f6e\u5728\u7247\u5242\u652f\u67b6\u4e0a\uff0c\u6d41\u901a\u6c60\u5185\u5f84\u4e3a 12 mm \u88c5\u8f7d\u4e86\u73bb\u7483\u73e0\uff0c\u6d41\u901f\u4e3a 16 mL\/min\uff0c\u6e29\u5ea6\u4e3a 37\u00b0C\uff0c\u5e76\u5728 90 \u5206\u949f\u65f6\u6536\u96c6\u6837\u54c1\u3002PVT \u7684\u518d\u73b0\u6027\u901a\u8fc7\u6765\u81ea\u7b2c\u4e94\u4e2a\u5408\u4f5c\u8005\u7684\u6570\u636e\u5f97\u5230\u8bc1\u5b9e\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h3><span class=\"has-inline-color has-vivid-cyan-blue-color\">\u56fe1. \u836f\u7247\u52a0\u8f7d\u65b9\u5f0f<\/span><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img width=\"1024\" height=\"398\" src=\"\/wp-content\/uploads\/2024\/06\/USP4-PVT-01-1024x398.jpg\" alt=\"\" class=\"wp-image-18374\" srcset=\"\/wp-content\/uploads\/2024\/06\/USP4-PVT-01-1024x398.jpg 1024w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-01-300x116.jpg 300w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-01-768x298.jpg 768w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-01-1536x596.jpg 1536w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-01.jpg 1731w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h3><span class=\"has-inline-color has-vivid-cyan-blue-color\">\u56fe3. \u901a\u8fc7\u6570\u5b66\u6a21\u578b\u9884\u6d4b\u4e86\u56db\u4e2a\u53c2\u6570\u5bf9\u6c34\u6768\u9178\u6eb6\u51fa\u5ea6\u7684\u5f71\u54cd\u3002\u836f\u7247\u88c5\u8f7d\u6a21\u5f0f\u7684\u9996\u5b57\u6bcd\u7f29\u5199\u4e3a HWB\uff08\u5728\u88c5\u6709\u73bb\u7483\u73e0\u7684\u836f\u7247\u652f\u67b6\u4e0a\uff09\u3001HWOB\uff08\u5728\u6ca1\u6709\u73bb\u7483\u73e0\u7684\u7247\u5242\u652f\u67b6\u4e0a\uff09\uff0cT\uff08\u5728\u73bb\u7483\u73e0\u7684\u9876\u90e8\uff09\u548c E\uff08\u5305\u57cb\uff09<\/span><\/h3>\n\n\n\n<figure class=\"wp-block-image size-full\"><img width=\"794\" height=\"231\" src=\"\/wp-content\/uploads\/2024\/06\/USP4-PVT-02.jpg\" alt=\"\" class=\"wp-image-18375\" srcset=\"\/wp-content\/uploads\/2024\/06\/USP4-PVT-02.jpg 794w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-02-300x87.jpg 300w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-02-768x223.jpg 768w\" sizes=\"(max-width: 794px) 100vw, 794px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<h3><span class=\"has-inline-color has-vivid-cyan-blue-color\">\u88684. \u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea PVT \u521d\u6b65\u9a8c\u6536\u6807\u51c6<\/span><\/h3>\n\n\n\n<figure class=\"wp-block-image size-large\"><img width=\"1024\" height=\"561\" src=\"\/wp-content\/uploads\/2024\/06\/USP4-PVT-03-1024x561.jpg\" alt=\"\" class=\"wp-image-18376\" srcset=\"\/wp-content\/uploads\/2024\/06\/USP4-PVT-03-1024x561.jpg 1024w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-03-300x164.jpg 300w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-03-768x421.jpg 768w, \/wp-content\/uploads\/2024\/06\/USP4-PVT-03.jpg 1119w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><meta charset=\"utf-8\">&gt;&gt;<a href=\"https:\/\/dissolutiontech.com\/issues\/202405\/DT202405_A02.pdf\">\u70b9\u51fb\u6d4f\u89c8\u8be5\u5b8c\u6574\u6587\u7ae0<\/a><\/p>\n\n\n\n<hr class=\"wp-block-separator is-style-wide\"\/>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column is-vertically-aligned-center\" style=\"flex-basis:50%\">\n<p class=\"has-text-align-left\">\u60f3\u4e86\u89e3\u66f4\u591a\u65b9\u6848\u8be6\u60c5\uff0c<br>\u8bf7\u626b\u63cf\u4e8c\u7ef4\u7801\u8054\u7cfb\u529b\u626c\u5c0f\u52a9\u624b\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top\" style=\"flex-basis:65%\">\n<div class=\"wp-block-columns are-vertically-aligned-center\">\n<div class=\"wp-block-column is-vertically-aligned-center\" style=\"flex-basis:100%\">\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:100%\">\n<div class=\"wp-block-image\"><figure class=\"alignleft size-medium is-resized\"><img src=\"\/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code-300x296.png\" alt=\"\" class=\"wp-image-16373\" width=\"225\" height=\"222\" srcset=\"\/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code-300x296.png 300w, \/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code-768x758.png 768w, \/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code.png 982w\" sizes=\"(max-width: 225px) 100vw, 225px\" \/><\/figure><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator is-style-wide\"\/>\n\n\n\n<h2>\u66f4\u591a\u6587\u7ae0<\/h2>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container\">\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:100%\"><ul class=\"wp-block-latest-posts__list is-grid columns-2 has-dates wp-block-latest-posts\"><li><a href=\"https:\/\/www.nikyang.com\/news\/dissolution-nanosuspensions\/\">\u6eb6\u51fa\u5ea6\u7814\u7a76 | \u7eb3\u7c73\u6df7\u60ac\u6db2\u7684\u6eb6\u51fa\u5ea6\u6d4b\u8bd5<\/a><time datetime=\"2023-11-16T09:59:59+08:00\" class=\"wp-block-latest-posts__post-date\">2023-11-16<\/time><\/li>\n<li><a href=\"https:\/\/www.nikyang.com\/news\/event-china-pharma-university-2023\/\">\u529b\u626c\u643a\u6d41\u6c60\u6cd5\u6eb6\u51fa\u6280\u672f\u8d70\u8fdb\u8bfe\u5802<\/a><time datetime=\"2023-10-31T15:29:21+08:00\" class=\"wp-block-latest-posts__post-date\">2023-10-31<\/time><\/li>\n<li><a href=\"https:\/\/www.nikyang.com\/drug-discovery\/dissolution-on-oral-thin-films\/\">\u7a81\u7834\u6eb6\u51fa\u5c40\u9650\uff0c\u4ee5\u6d41\u6c60\u6cd5\u52a9\u529b\u53e3\u6eb6\u819c\u5236\u5242\u7814\u53d1<\/a><time datetime=\"2023-10-17T16:58:38+08:00\" class=\"wp-block-latest-posts__post-date\">2023-10-17<\/time><\/li>\n<li><a href=\"https:\/\/www.nikyang.com\/news\/event-bceia-2023\/\">BCEIA 2023 \u5b8c\u7f8e\u6536\u5b98 | \u529b\u626c\u4f01\u4e1a\u52a9\u60a8\u8fc8\u5411\u667a\u6167\u79d1\u7814\u65b0\u65f6\u4ee3\uff01<\/a><time datetime=\"2023-09-15T12:08:45+08:00\" class=\"wp-block-latest-posts__post-date\">2023-09-15<\/time><\/li>\n<\/ul>\n\n\n<p><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u5173\u6ce8\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u6027\u80fd\u9a8c\u8bc1\u7684\u5c0f\u4f19\u4f34\u8d76\u7d27\u8fc7\u6765\u56f4\u89c2\uff01\u5728\u300aDissolution Technology\u300b\u5168\u65b0\u4e00\u671f\u671f\u520a\u4e2d\uff0c\u520a\u5370\u4e86\u4e00\u7bc7\u9898\u4e3a\u201cApplication of Salicylic Acid Tablets in the Performance Verification Test for the Flow-Through Cell Apparatus\u201d\uff08\u6c34\u6768\u9178\u6821\u6b63\u7247\u5728\u6d41\u6c60\u6cd5\u4eea\u5668\u6027\u80fd\u9a8c\u8bc1\u4e2d\u7684\u5e94\u7528\uff09\u7684\u6587\u7ae0\uff0c\u8fd9\u5bf9\u4e8e\u56fd\u5185\u4f7f\u7528\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u7684\u4e1a\u754c\u540c\u4ec1\u6765\u8bf4\u65e0\u7591\u662f\u4e00\u4e2a\u632f\u594b\u4eba\u5fc3\u7684\u597d\u6d88\u606f\u3002\u6d41\u6c60\u6cd5\u6eb6\u51fa\u4eea\u5982\u4f55\u6267\u884c\u6027\u80fd\u9a8c\u8bc1\u4e00\u76f4\u662f\u4e1a\u754c\u70ed\u95e8\u63a2\u8ba8\u7684\u8bdd\u9898\uff0c\u56fd\u9645\u56fd\u5185\u5747\u65e0\u53ef\u53c2\u8003\u6807\u51c6\u3002\u8be5\u6587\u7ae0\u7684\u53d1\u8868\uff0c\u4e3a\u4e1a\u754c\u6307\u5f15\u4e86\u53ef\u53c2\u8003\u7684\u65b9\u5411\u3002\u70b9\u51fb\u6d4f\u89c8\u8be5\u5b8c\u6574\u6587\u7ae0\u3002 \u6587\u7ae0\u6458\u8981\uff1a 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