{"id":18216,"date":"2023-12-22T10:12:00","date_gmt":"2023-12-22T02:12:00","guid":{"rendered":"https:\/\/www.nikyang.com\/?p=18216"},"modified":"2024-01-02T10:15:13","modified_gmt":"2024-01-02T02:15:13","slug":"sweeter-sucralose-hptlc-analysis","status":"publish","type":"post","link":"https:\/\/www.nikyang.com\/news\/sweeter-sucralose-hptlc-analysis\/","title":{"rendered":"\u4ee3\u7cd6\uff1a\u751c\u871c\u7684\u9677\u9631\uff1f|\u8584\u5c42\u8272\u8c31\u6cd5\u9ad8\u7075\u654f\u5ea6\u68c0\u6d4b\u4e09\u6c2f\u8517\u7cd6"},"content":{"rendered":"\n<p>\u968f\u7740\u793e\u4f1a\u7ecf\u6d4e\u7684\u53d1\u5c55\u53d8\u5316\uff0c\u4e16\u754c\u80fd\u6e90\u7ed3\u6784\u53d1\u751f\u4e86\u6df1\u523b\u53d8\u5316\u3002\u65b0\u80fd\u6e90\u6b63\u8fce\u6765\u7206\u53d1\u5f0f\u589e\u957f\uff0c\u65b0\u80fd\u6e90\u8f66\u3001\u52a8\u529b\u7535\u6c60\u7b49\u9886\u57df\u7684\u5e02\u5f88\u5feb\u53c8\u6765\u5230\u4e00\u5e74\u7684\u5c3e\u58f0\uff0c\u51ac\u81f3\u3001\u8de8\u5e74\u4ee5\u53ca\u4e00\u7cfb\u5217\u503c\u5f97\u6b22\u5e86\u7684\u8282\u65e5\u63a5\u8e35\u800c\u6765\u3002\u4e0e\u4eb2\u670b\u597d\u53cb\u7684\u6b22\u805a \u2014\u2014 \u4eab\u7528\u7f8e\u98df\u7edd\u5bf9\u662f\u59a5\u59a5\u7684 C \u4f4d\u8282\u76ee\u3002\u7136\u800c\uff0c\u5728\u5c3d\u60c5\u4eab\u53d7\u7f8e\u98df\u7684\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u4e0d\u8981\u5ffd\u7565\u81ea\u5df1\u7684\u8eab\u4f53\u54e6\uff01\u6ce8\u610f\u907f\u514d\u589e\u52a0\u8eab\u4f53\u7684\u8d1f\u62c5\uff0c\u6bd4\u5982\u9ad8\u7cd6\u5206\u7684\u98df\u54c1\u6444\u5165\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img width=\"1024\" height=\"575\" src=\"\/wp-content\/uploads\/2024\/01\/640-1024x575.jpg\" alt=\"\" class=\"wp-image-18217\" srcset=\"\/wp-content\/uploads\/2024\/01\/640-1024x575.jpg 1024w, \/wp-content\/uploads\/2024\/01\/640-300x168.jpg 300w, \/wp-content\/uploads\/2024\/01\/640-768x431.jpg 768w, \/wp-content\/uploads\/2024\/01\/640.jpg 1080w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p>\u8fd1\u5e74 \u201c\u63a7\u7cd6\u201d \u6210\u4e3a\u4e86\u4e00\u79cd\u65b0\u65f6\u5c1a\uff0c\u8d8a\u6765\u8d8a\u591a\u4eba\u5f00\u59cb\u5173\u6ce8\u7cd6\u5206\u6444\u5165\uff0c\u751a\u81f3\u628a\u7cd6\u5206\u89c6\u4e3a\u996e\u98df\u4e2d\u7684 \u201c\u5934\u53f7\u5927\u9b54\u5934\u201d\uff0c\u5546\u5bb6\u4eec\u4e5f\u5728\u79ef\u6781\u7814\u7a76\u5404\u79cd\u751c\u5473\u5242\u6210\u5206\uff0c\u6253\u9020 \u201c\u65e0\u7cd6\u201d \u4ea7\u54c1\uff0c\u5438\u5f15\u6d88\u8d39\u8005\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong><span class=\"has-inline-color has-vivid-cyan-blue-color\">\u4ee3\u7cd6\uff1a\u751c\u871c\u7684\u9677\u9631\uff1f<\/span><\/strong><\/p>\n\n\n\n<p>\u7136\u800c\u4e0d\u4e45\u524d\uff0c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u4e0b\u5c5e\u7684\u56fd\u9645\u764c\u75c7\u7814\u7a76\u673a\u6784\u5ba3\u5e03\u4e86\u4e00\u79cd\u5e38\u7528\u7684\u751c\u5473\u5242 &#8211; \u963f\u65af\u5df4\u751c\u4e3a \u201c\u53ef\u80fd\u81f4\u764c\u7269\u201d\uff0c\u6d88\u606f\u4e00\u51fa\uff0c\u5173\u4e8e\u751c\u5473\u5242\u5065\u5eb7\u4e0e\u5426\u7684\u4e89\u8bae\u767b\u4e0a\u70ed\u641c\u3002<\/p>\n\n\n\n<p>\u963f\u65af\u5df4\u751c\u8fd9\u79cd\u4ee3\u7cd6\u5728\u6211\u4eec\u7684\u996e\u6599\u3001\u5976\u8336\u3001\u86cb\u7cd5\u4e2d\u5e7f\u6cdb\u4f7f\u7528\uff0c\u76f8\u5e94\u7684\u5404\u79cd\u4ee3\u7cd6\u5728\u52a0\u5de5\u98df\u54c1\u4e2d\u7684\u542b\u91cf\u5f15\u8d77\u5e7f\u6cdb\u5173\u6ce8\u3002\u4e8b\u5b9e\u4e0a\uff0c\u4eba\u5de5\u5408\u6210\u751c\u5473\u5242\u53d1\u5c55\u81f3\u4eca\u5df2\u6709\u516d\u4ee3\uff0c\u4f9d\u6b21\u4e3a\u7cd6\u7cbe\u3001\u751c\u871c\u7d20\u3001\u963f\u65af\u5df4\u751c\u3001\u5b89\u8d5b\u871c\u3001\u4e09\u6c2f\u8517\u7cd6\u3001\u7ebd\u751c\u3002\u800c\u4e94\u4ee3\u751c\u5473\u5242\u4e09\u6c2f\u8517\u7cd6\u5177\u6709\u7a33\u5b9a\u6027\u9ad8\u3001\u4eb2\u6c34\u6027\u5f3a\u3001\u9ad8\u751c\u5ea6\u3001\u7eaf\u6b63\u751c\u5473\u3001\u5b89\u5168\u7b49\u4f18\u70b9\uff0c\u4e14\u751c\u5ea6\u66f2\u7ebf\u4e0e\u7b2c\u56db\u4ee3\u5b89\u8d5b\u871c\u8f83\u4e3a\u63a5\u8fd1\uff0c\u662f\u4ee3\u7cd6\u4e2d\u7684\u4e0d\u4e8c\u9009\u62e9\u3002(\u5f15\u81ea\u65b0\u6d6a\u8d22\u7ecf)<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img width=\"847\" height=\"494\" src=\"\/wp-content\/uploads\/2024\/01\/640-2.jpg\" alt=\"\" class=\"wp-image-18218\" srcset=\"\/wp-content\/uploads\/2024\/01\/640-2.jpg 847w, \/wp-content\/uploads\/2024\/01\/640-2-300x175.jpg 300w, \/wp-content\/uploads\/2024\/01\/640-2-768x448.jpg 768w\" sizes=\"(max-width: 847px) 100vw, 847px\" \/><figcaption><sup>\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u516c\u5e03\u963f\u65af\u5df4\u751c\u5371\u5bb3\u548c\u98ce\u9669\u8bc4\u4f30\u7ed3\u679c<\/sup><\/figcaption><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p>\u8fd1\u5e74\u6765\uff0c\u5173\u4e8e\u4e09\u6c2f\u8517\u7cd6\u5b89\u5168\u6027\u7684\u8ba8\u8bba\u5176\u5b9e\u4e5f\u662f\u4e89\u8bae\u4e0d\u65ad\uff0c\u6709\u7814\u7a76\u79f0\uff0c\u957f\u671f\u98df\u7528\u4e09\u6c2f\u8517\u7cd6\uff0c\u53ef\u80fd\u4f1a\u4ea7\u751f\u6f5c\u5728\u7684\u4e0d\u826f\u5f71\u54cd\uff0c\u4f8b\u5982\u6210\u4eba\u60a3 2 \u578b\u7cd6\u5c3f\u75c5\u3001\u5fc3\u8840\u7ba1\u75be\u75c5\u548c\u6b7b\u4ea1\u7387\u7684\u98ce\u9669\u589e\u52a0\u3002<\/p>\n\n\n\n<p>\u5355\u5355\u79bb\u5f00\u5242\u91cf\u8c08\u6bd2\u6027\u90fd\u662f\u4e0d\u5ba2\u89c2\u7684\uff0c\u90a3\u4e48\u6211\u4eec\u5e94\u8be5\u5982\u4f55\u5b9e\u73b0\u542b\u4ee3\u7cd6 (\u5982\u4e09\u6c2f\u8517\u7cd6) \u4ea7\u54c1\u7684\u9650\u91cf\u6444\u5165\uff0c\u4ee5\u53ca\u5bf9\u5176\u542b\u91cf\u5b9e\u73b0\u5feb\u901f\u800c\u6709\u6548\u7684\u68c0\u6d4b\u5462\uff1f<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong><span class=\"has-inline-color has-vivid-cyan-blue-color\"><strong><meta charset=\"utf-8\"><strong><span class=\"has-inline-color has-vivid-cyan-blue-color\"><strong>\u68c0\u6d4b\u4e09\u6c2f\u8517\u7cd6\u7684\u96be\u70b9<\/strong><\/span><\/strong><\/strong><\/span><\/strong><\/p>\n\n\n\n<p>\u7531\u4e8e\u4e09\u6c2f\u8517\u7cd6\u7d2b\u5916\u5438\u6536\u5f31 (\u2264200nm)\uff0c\u7f3a\u4e4f\u751f\u8272\u56e2\uff0c\u6240\u4ee5\u5206\u6790\u98df\u54c1\u4e2d\u7684\u4e09\u6c2f\u8517\u7cd6\u662f\u76f8\u5f53\u56f0\u96be\u3002\u4e00\u822c\u4f1a\u5229\u7528 RP-HPLC \u65b9\u6cd5\u91c7\u7528\u6298\u5c04\u7387\u68c0\u6d4b [1\u20133] \u6216 192nm[4] \u6216 200nm[3] \u5904\u7684\u7d2b\u5916\u7ebf\u5438\u6536\u3002\u53ef\u662f\uff0c\u8fd9\u79cd\u5728\u4f4e\u6ce2\u957f\u8303\u56f4\u5185\u7684\u68c0\u6d4b\u4e13\u5c5e\u6027\u4f4e\uff0c\u5e72\u6270\u4fe1\u53f7\u591a\uff0c\u9700\u8981\u590d\u6742\u7684\u6837\u54c1\u524d\u5904\u7406\u4ee5\u6d88\u9664\u5e72\u6270\u57fa\u8d28\u6210\u5206\u3002\u5f53\u7136\uff0c\u6211\u4eec\u4e5f\u53ef\u4ee5\u91c7\u7528\u5bf9\u785d\u57fa\u82ef\u7532\u9170\u6c2f\u67f1\u524d\u884d\u751f\u5904\u7406\uff0c\u518d\u5728 260nm \u5904\u68c0\u6d4b\u4e09\u6c2f\u8517\u7cd6\uff0c\u5f97\u5230\u5177\u6709\u5f3a\u7d2b\u5916\u5438\u6536\u7684\u884d\u751f\u7269\uff0c\u63d0\u9ad8\u68c0\u6d4b\u7684\u7075\u654f\u5ea6\u548c\u7279\u5f02\u6027\uff0c\u4f46\u662f\u8fd9\u4f1a\u5bfc\u81f4\u975e\u5e38\u5197\u957f\u7684 HPLC \u65b9\u6cd5\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><meta charset=\"utf-8\"><strong><span class=\"has-inline-color has-vivid-cyan-blue-color\"><strong><strong>\u4ee5\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5\u68c0\u6d4b\u4e09\u6c2f\u8517\u7cd6<\/strong><\/strong><\/span><\/strong><\/p>\n\n\n\n<p>\u548c HPLC \u65b9\u6cd5\u76f8\u6bd4\uff0c\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5 (HPTLC) \u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86\u66f4\u52a0\u4fbf\u6377\u3001\u53ef\u9760\u3001\u4f4e\u6210\u672c\u7684\u89e3\u51b3\u65b9\u6848\u3002<strong>\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5\u53ef\u4ee5\u7528\u4e8e\u4e09\u6c2f\u8517\u7cd6\u548c\u679c\u7cd6\u7b49\u591a\u79cd\u98df\u54c1\u57fa\u8d28\u548c\u996e\u6599\u7684\u5b9a\u91cf\uff0c\u5728\u68c0\u6d4b\u996e\u6599\u7c7b\u578b\u7684\u6837\u54c1\u65f6\uff0c\u751a\u81f3\u65e0\u9700\u8fdb\u884c\u6837\u54c1\u5236\u5907\u3002<\/strong><\/p>\n\n\n\n<p>\u8584\u5c42\u8272\u8c31\u7684\u5f00\u653e\u6027\u4f7f\u5176\u5177\u6709\u5e7f\u6cdb\u9002\u7528\u6027\uff0c\u80fd\u8f7b\u677e\u641e\u5b9a\u5404\u79cd\u5e38\u89c1\u7684\u98df\u54c1\u4f9b\u8bd5\u54c1\uff0c\u4f8b\u5982\u725b\u5976\u86cb\u7cd5\u3001\u4e0d\u540c\u79cd\u7c7b\u7684\u997c\u5e72\u3001\u5de7\u514b\u529b\u86cb\u7cd5\u3001\u53ef\u4e50\u3001\u725b\u5976\u3001\u786c\u7cd6\u548c\u80fd\u91cf\u6216\u8fd0\u52a8\u996e\u6599\u7b49\u3002\u672c\u793a\u4f8b\u4e2d\uff0c\u542b\u91cf\u6d4b\u5b9a\u65b9\u6cd5\u7684\u68c0\u6d4b\u9650 (LOD):\u5728 366 \/ 400nm\u3001405nm \u548c 500nm \u5904\u5206\u522b\u4e3a 4\u30018 \u548c 5ng\/\u6761\u5e26\uff0cRSD\u22644.4% (n=3)\u3002\u901a\u8fc7\u4f7f\u7528\u82ef\u80fa\u4e8c\u82ef\u80fa\u6b63\u78f7\u9178\u8bd5\u5242\u8272\u8c31\u540e\u884d\u751f\u5316\u751a\u81f3\u83b7\u5f97\u4e86\u6781\u4f73\u7684\u7279\u5f02\u6027\uff0c\u65e0\u8bba\u4f9b\u8bd5\u54c1\u4e2d\u542b\u6709\u591a\u4e48\u590d\u6742\u7684\u78b3\u6c34\u5316\u5408\u7269\u548c\u5176\u4ed6\u57fa\u8d28\u6210\u5206\uff0c\u53ea\u6709\u4e09\u6c2f\u8517\u7cd6\u884d\u751f\u540e\u4f1a\u4ea7\u751f\u53ef\u68c0\u6d4b\u8367\u5149\u3002\u6b64\u5916\uff0c\u901a\u8fc7 TLC-MS \u539f\u4f4d\u68c0\u6d4b\u53ef\u8fdb\u4e00\u6b65\u63d0\u9ad8\u68c0\u6d4b\u7075\u654f\u5ea6\u4e14\u540c\u65f6\u83b7\u5f97\u66f4\u591a\u7ed3\u6784\u4fe1\u606f\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img width=\"610\" height=\"532\" src=\"\/wp-content\/uploads\/2024\/01\/640-5.png\" alt=\"\" class=\"wp-image-18219\" srcset=\"\/wp-content\/uploads\/2024\/01\/640-5.png 610w, \/wp-content\/uploads\/2024\/01\/640-5-300x262.png 300w\" sizes=\"(max-width: 610px) 100vw, 610px\" \/><figcaption><sup>\u68c0\u6d4b\u7ed3\u679c 1: \u996e\u6599\u4e2d\u751c\u5473\u5242\u4e09\u6c2f\u8517\u7cd6\u7684\u68c0\u6d4b\u00a0\u2014\u2014 \u65e0\u9700\u6837\u54c1\u5236\u5907<\/sup><\/figcaption><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img width=\"843\" height=\"553\" src=\"\/wp-content\/uploads\/2024\/01\/640-6.png\" alt=\"\" class=\"wp-image-18220\" srcset=\"\/wp-content\/uploads\/2024\/01\/640-6.png 843w, \/wp-content\/uploads\/2024\/01\/640-6-300x197.png 300w, \/wp-content\/uploads\/2024\/01\/640-6-768x504.png 768w\" sizes=\"(max-width: 843px) 100vw, 843px\" \/><figcaption><sup>\u68c0\u6d4b\u7ed3\u679c 2.1: \u751c\u54c1\u4e2d\u751c\u5473\u5242\u4e09\u6c2f\u8517\u7cd6\u7684\u68c0\u6d4b\u00a0\u2014\u2014 \u7b80\u5355\u6837\u54c1\u5236\u5907<\/sup><\/figcaption><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img src=\"\/wp-content\/uploads\/2024\/01\/640-7.png\" alt=\"\" class=\"wp-image-18221\" width=\"791\" height=\"489\" srcset=\"\/wp-content\/uploads\/2024\/01\/640-7.png 791w, \/wp-content\/uploads\/2024\/01\/640-7-300x185.png 300w, \/wp-content\/uploads\/2024\/01\/640-7-768x475.png 768w\" sizes=\"(max-width: 791px) 100vw, 791px\" \/><figcaption><sup>\u68c0\u6d4b\u7ed3\u679c 2.2: \u751c\u54c1\u4e2d\u751c\u5473\u5242\u4e09\u6c2f\u8517\u7cd6\u7684\u68c0\u6d4b\u2014\u2014 TLC-MS \u8054\u7528<\/sup><\/figcaption><\/figure>\n\n\n\n<p><\/p>\n\n\n\n<p><strong><span class=\"has-inline-color has-vivid-cyan-blue-color\">\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5\u7684\u4f18\u52bf<\/span><\/strong><\/p>\n\n\n\n<p>\u901a\u8fc7\u4e09\u6c2f\u8517\u7cd6\u7684 HPTLC \u7684\u68c0\u6d4b\u793a\u4f8b\uff0c\u53ef\u4ee5\u770b\u5230\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5\u5177\u6709\u6837\u54c1\u5236\u5907\u7b80\u5355\u3001\u6837\u54c1\u517c\u5bb9\u6027\u597d\u3001\u884d\u751f\u5316\u5904\u7406\u7b80\u5355\u548c\u68c0\u6d4b\u7075\u654f\u5ea6\u9ad8\u7684\u4f18\u52bf\uff0c\u540c\u65f6\u8fd8\u9002\u7528\u4e8e\u5927\u91cf\u6837\u54c1\u7684\u9ad8\u901a\u91cf\u5e73\u884c\u5feb\u901f\u5206\u6790\u3002<\/p>\n\n\n\n<p>\u8fd1\u5e74\uff0c\u4e13\u4e1a\u8584\u5c42\u8272\u8c31\u6280\u672f\u5f15\u9886\u8005 CAMAG \u516c\u53f8\u63a8\u51fa\u7684 HPTLC PRO \u5168\u81ea\u52a8\u8584\u5c42\u68c0\u6d4b\u7cfb\u7edf\uff0c\u66f4\u5c06\u8584\u5c42\u8272\u8c31\u6280\u672f\u63d0\u5347\u5230\u65b0\u7684\u9ad8\u5ea6\uff0c<strong>\u5b9e\u73b0\u4e86\u5168\u7a0b\u65e0\u4eba\u5e72\u9884\u7684\u81ea\u52a8\u5316\u8fde\u7eed\u591a\u677f\u7684\u81ea\u52a8\u5316\u5206\u6790\u6d41\u7a0b \u2014\u2014 \u201c\u70b9\u6837 \u2013 \u5c55\u5f00 \u2013 \u884d\u751f \u2013 \u68c0\u6d4b \u2013 \u5206\u6790 \u2013 \u62a5\u544a\u201d \u4e00\u7ad9\u5f0f\u68c0\u6d4b\uff0c\u540c\u65f6\u5b9e\u73b0\u5168\u6d41\u7a0b\u6570\u5b57\u5316\u7ba1\u7406\uff0c\u653b\u514b\u8584\u5c42\u8272\u8c31\u6280\u672f\u91cd\u73b0\u96be\u7684\u74f6\u9888\u95ee\u9898\u3002<\/strong><\/p>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\">\n<figure class=\"wp-block-image size-full\"><img width=\"440\" height=\"248\" src=\"\/wp-content\/uploads\/2024\/01\/640-3.gif\" alt=\"\" class=\"wp-image-18222\"\/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column\">\n<figure class=\"wp-block-image size-full\"><img width=\"440\" height=\"248\" src=\"\/wp-content\/uploads\/2024\/01\/640-4.gif\" alt=\"\" class=\"wp-image-18223\"\/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<p>\u8584\u5c42\u8272\u8c31\u4e0e\u6db2\u76f8\u8272\u8c31\u548c\u6c14\u76f8\u8272\u8c31\u4e00\u6837\uff0c\u90fd\u5c5e\u4e8e\u5fae\u91cf\u5206\u6790\u8272\u8c31\uff0c\u5728\u79d1\u7814\u548c\u5e38\u89c4\u68c0\u6d4b\u4e2d\u626e\u6f14\u7740\u91cd\u8981\u89d2\u8272\uff0c\u5c24\u5176\u9002\u7528\u4e8e\u590d\u6742\u6df7\u5408\u7269\u5feb\u901f\u5206\u79bb\u3002\u9664\u4e86\u4e09\u6c2f\u8517\u7cd6\u4ee5\u5916\uff0c\u8584\u5c42\u8272\u8c31\u8fd8\u53ef\u7528\u4e8e\u68c0\u6d4b\u98df\u54c1\u4e2d\u7684\u5404\u7c7b\u6dfb\u52a0\u5242\uff0c\u5982\u4eba\u5de5\u8272\u7d20\u548c\u9999\u7cbe\uff0c\u4e5f\u53ef\u7528\u4e8e\u519c\u4ea7\u54c1\u3001\u836f\u54c1\u3001\u7cbe\u7ec6\u5316\u5de5\u4ea7\u54c1\u4e2d\uff0c\u6d4b\u9a8c\u519c\u836f\u6b8b\u7559\u3001\u6742\u8d28\u548c\u6709\u5bb3\u7269\u8d28\u7b49\u7b49\uff0c\u5e94\u7528\u9886\u57df\u5341\u5206\u5e7f\u6cdb\u3002<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p class=\"has-text-align-center\"><em>\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5\u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86<\/em><\/p>\n\n\n\n<p class=\"has-text-align-center\"><em>\u5feb\u6377\u3001\u4f4e\u6210\u672c\u3001\u9ad8\u901a\u91cf\u7684\u68c0\u6d4b\u65b9\u6cd5\u3002<\/em><\/p>\n\n\n\n<p class=\"has-text-align-center\"><em>\u968f\u7740\u7ed3\u5408\u81ea\u52a8\u5316\u53ca\u6570\u5b57\u5316\u7684\u6280\u672f\u5347\u7ea7\uff0c<\/em><\/p>\n\n\n\n<p class=\"has-text-align-center\"><em>\u8584\u5c42\u8272\u8c31\u6280\u672f\u4f1a\u66f4\u597d\u5730<\/em><\/p>\n\n\n\n<p class=\"has-text-align-center\"><em>\u5e2e\u52a9\u6211\u4eec\u5173\u6ce8\u98df\u54c1\u8d28\u63a7\uff0c<\/em><\/p>\n\n\n\n<p class=\"has-text-align-center\"><em>\u8ba9\u6211\u4eec\u62e5\u62b1\u66f4\u5065\u5eb7\u3001\u66f4\u9ad8\u8d28\u91cf\u7684\u751f\u6d3b\uff01<\/em><\/p>\n\n\n\n<hr class=\"wp-block-separator is-style-wide\"\/>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column is-vertically-aligned-center\" style=\"flex-basis:50%\">\n<p class=\"has-text-align-left\">\u60f3\u4e86\u89e3\u66f4\u591a\u65b9\u6848\u8be6\u60c5\uff0c<br>\u8bf7\u626b\u63cf\u4e8c\u7ef4\u7801\u8054\u7cfb\u529b\u626c\u5c0f\u52a9\u624b\u3002<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-top\" style=\"flex-basis:65%\">\n<div class=\"wp-block-columns are-vertically-aligned-center\">\n<div class=\"wp-block-column is-vertically-aligned-center\" style=\"flex-basis:100%\">\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:100%\">\n<div class=\"wp-block-image\"><figure class=\"alignleft size-medium is-resized\"><img src=\"\/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code-300x296.png\" alt=\"\" class=\"wp-image-16373\" width=\"225\" height=\"222\" srcset=\"\/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code-300x296.png 300w, \/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code-768x758.png 768w, \/wp-content\/uploads\/2022\/06\/\u529b\u626c\u5c0f\u52a9\u624b-QR-Code.png 982w\" sizes=\"(max-width: 225px) 100vw, 225px\" \/><\/figure><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator is-style-wide\"\/>\n\n\n\n<h2>\u66f4\u591a\u6587\u7ae0<\/h2>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:100%\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container\">\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:100%\"><ul class=\"wp-block-latest-posts__list is-grid columns-2 has-dates wp-block-latest-posts\"><li><a href=\"https:\/\/www.nikyang.com\/news\/dissolution-nanosuspensions\/\">\u6eb6\u51fa\u5ea6\u7814\u7a76 | \u7eb3\u7c73\u6df7\u60ac\u6db2\u7684\u6eb6\u51fa\u5ea6\u6d4b\u8bd5<\/a><time datetime=\"2023-11-16T09:59:59+08:00\" class=\"wp-block-latest-posts__post-date\">2023-11-16<\/time><\/li>\n<li><a href=\"https:\/\/www.nikyang.com\/news\/event-china-pharma-university-2023\/\">\u529b\u626c\u643a\u6d41\u6c60\u6cd5\u6eb6\u51fa\u6280\u672f\u8d70\u8fdb\u8bfe\u5802<\/a><time datetime=\"2023-10-31T15:29:21+08:00\" class=\"wp-block-latest-posts__post-date\">2023-10-31<\/time><\/li>\n<li><a href=\"https:\/\/www.nikyang.com\/drug-discovery\/dissolution-on-oral-thin-films\/\">\u7a81\u7834\u6eb6\u51fa\u5c40\u9650\uff0c\u4ee5\u6d41\u6c60\u6cd5\u52a9\u529b\u53e3\u6eb6\u819c\u5236\u5242\u7814\u53d1<\/a><time datetime=\"2023-10-17T16:58:38+08:00\" class=\"wp-block-latest-posts__post-date\">2023-10-17<\/time><\/li>\n<li><a href=\"https:\/\/www.nikyang.com\/news\/event-bceia-2023\/\">BCEIA 2023 \u5b8c\u7f8e\u6536\u5b98 | \u529b\u626c\u4f01\u4e1a\u52a9\u60a8\u8fc8\u5411\u667a\u6167\u79d1\u7814\u65b0\u65f6\u4ee3\uff01<\/a><time datetime=\"2023-09-15T12:08:45+08:00\" class=\"wp-block-latest-posts__post-date\">2023-09-15<\/time><\/li>\n<\/ul>\n\n\n<p><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u968f\u7740\u793e\u4f1a\u7ecf\u6d4e\u7684\u53d1\u5c55\u53d8\u5316\uff0c\u4e16\u754c\u80fd\u6e90\u7ed3\u6784\u53d1\u751f\u4e86\u6df1\u523b\u53d8\u5316\u3002\u65b0\u80fd\u6e90\u6b63\u8fce\u6765\u7206\u53d1\u5f0f\u589e\u957f\uff0c\u65b0\u80fd\u6e90\u8f66\u3001\u52a8\u529b\u7535\u6c60\u7b49\u9886\u57df\u7684\u5e02\u5f88\u5feb\u53c8\u6765\u5230\u4e00\u5e74\u7684\u5c3e\u58f0\uff0c\u51ac\u81f3\u3001\u8de8\u5e74\u4ee5\u53ca\u4e00\u7cfb\u5217\u503c\u5f97\u6b22\u5e86\u7684\u8282\u65e5\u63a5\u8e35\u800c\u6765\u3002\u4e0e\u4eb2\u670b\u597d\u53cb\u7684\u6b22\u805a \u2014\u2014 \u4eab\u7528\u7f8e\u98df\u7edd\u5bf9\u662f\u59a5\u59a5\u7684 C \u4f4d\u8282\u76ee\u3002\u7136\u800c\uff0c\u5728\u5c3d\u60c5\u4eab\u53d7\u7f8e\u98df\u7684\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u4e0d\u8981\u5ffd\u7565\u81ea\u5df1\u7684\u8eab\u4f53\u54e6\uff01\u6ce8\u610f\u907f\u514d\u589e\u52a0\u8eab\u4f53\u7684\u8d1f\u62c5\uff0c\u6bd4\u5982\u9ad8\u7cd6\u5206\u7684\u98df\u54c1\u6444\u5165\u3002 \u8fd1\u5e74 \u201c\u63a7\u7cd6\u201d \u6210\u4e3a\u4e86\u4e00\u79cd\u65b0\u65f6\u5c1a\uff0c\u8d8a\u6765\u8d8a\u591a\u4eba\u5f00\u59cb\u5173\u6ce8\u7cd6\u5206\u6444\u5165\uff0c\u751a\u81f3\u628a\u7cd6\u5206\u89c6\u4e3a\u996e\u98df\u4e2d\u7684 \u201c\u5934\u53f7\u5927\u9b54\u5934\u201d\uff0c\u5546\u5bb6\u4eec\u4e5f\u5728\u79ef\u6781\u7814\u7a76\u5404\u79cd\u751c\u5473\u5242\u6210\u5206\uff0c\u6253\u9020 \u201c\u65e0\u7cd6\u201d \u4ea7\u54c1\uff0c\u5438\u5f15\u6d88\u8d39\u8005\u3002 \u4ee3\u7cd6\uff1a\u751c\u871c\u7684\u9677\u9631\uff1f \u7136\u800c\u4e0d\u4e45\u524d\uff0c\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u4e0b\u5c5e\u7684\u56fd\u9645\u764c\u75c7\u7814\u7a76\u673a\u6784\u5ba3\u5e03\u4e86\u4e00\u79cd\u5e38\u7528\u7684\u751c\u5473\u5242 &#8211; \u963f\u65af\u5df4\u751c\u4e3a \u201c\u53ef\u80fd\u81f4\u764c\u7269\u201d\uff0c\u6d88\u606f\u4e00\u51fa\uff0c\u5173\u4e8e\u751c\u5473\u5242\u5065\u5eb7\u4e0e\u5426\u7684\u4e89\u8bae\u767b\u4e0a\u70ed\u641c\u3002 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(\u2264200nm)\uff0c\u7f3a\u4e4f\u751f\u8272\u56e2\uff0c\u6240\u4ee5\u5206\u6790\u98df\u54c1\u4e2d\u7684\u4e09\u6c2f\u8517\u7cd6\u662f\u76f8\u5f53\u56f0\u96be\u3002\u4e00\u822c\u4f1a\u5229\u7528 RP-HPLC \u65b9\u6cd5\u91c7\u7528\u6298\u5c04\u7387\u68c0\u6d4b [1\u20133] \u6216 192nm[4] \u6216 200nm[3] \u5904\u7684\u7d2b\u5916\u7ebf\u5438\u6536\u3002\u53ef\u662f\uff0c\u8fd9\u79cd\u5728\u4f4e\u6ce2\u957f\u8303\u56f4\u5185\u7684\u68c0\u6d4b\u4e13\u5c5e\u6027\u4f4e\uff0c\u5e72\u6270\u4fe1\u53f7\u591a\uff0c\u9700\u8981\u590d\u6742\u7684\u6837\u54c1\u524d\u5904\u7406\u4ee5\u6d88\u9664\u5e72\u6270\u57fa\u8d28\u6210\u5206\u3002\u5f53\u7136\uff0c\u6211\u4eec\u4e5f\u53ef\u4ee5\u91c7\u7528\u5bf9\u785d\u57fa\u82ef\u7532\u9170\u6c2f\u67f1\u524d\u884d\u751f\u5904\u7406\uff0c\u518d\u5728 260nm \u5904\u68c0\u6d4b\u4e09\u6c2f\u8517\u7cd6\uff0c\u5f97\u5230\u5177\u6709\u5f3a\u7d2b\u5916\u5438\u6536\u7684\u884d\u751f\u7269\uff0c\u63d0\u9ad8\u68c0\u6d4b\u7684\u7075\u654f\u5ea6\u548c\u7279\u5f02\u6027\uff0c\u4f46\u662f\u8fd9\u4f1a\u5bfc\u81f4\u975e\u5e38\u5197\u957f\u7684 HPLC \u65b9\u6cd5\u3002 \u4ee5\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5\u68c0\u6d4b\u4e09\u6c2f\u8517\u7cd6 \u548c HPLC \u65b9\u6cd5\u76f8\u6bd4\uff0c\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5 (HPTLC) \u4e3a\u6211\u4eec\u63d0\u4f9b\u4e86\u66f4\u52a0\u4fbf\u6377\u3001\u53ef\u9760\u3001\u4f4e\u6210\u672c\u7684\u89e3\u51b3\u65b9\u6848\u3002\u9ad8\u6548\u8584\u5c42\u8272\u8c31\u6cd5\u53ef\u4ee5\u7528\u4e8e\u4e09\u6c2f\u8517\u7cd6\u548c\u679c\u7cd6\u7b49\u591a\u79cd\u98df\u54c1\u57fa\u8d28\u548c\u996e\u6599\u7684\u5b9a\u91cf\uff0c\u5728\u68c0\u6d4b\u996e\u6599\u7c7b\u578b\u7684\u6837\u54c1\u65f6\uff0c\u751a\u81f3\u65e0\u9700\u8fdb\u884c\u6837\u54c1\u5236\u5907\u3002 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