{"id":17792,"date":"2023-06-23T12:26:16","date_gmt":"2023-06-23T04:26:16","guid":{"rendered":"https:\/\/www.nikyang.com\/?p=17792"},"modified":"2023-06-23T12:27:07","modified_gmt":"2023-06-23T04:27:07","slug":"dbs-animal_biomarker-case","status":"publish","type":"post","link":"https:\/\/www.nikyang.com\/bio-sample-prep\/dbs-animal_biomarker-case\/","title":{"rendered":"DBS \u5e72\u8840\u6591\u5e94\u7528\u7279\u96c6 3: \u52a8\u7269\u75be\u75c5\u7684\u751f\u7269\u6807\u8bb0\u7269"},"content":{"rendered":"\t\t
\u9aa8\u8d28\u758f\u677e\u662f\u4e00\u79cd\u5f71\u54cd\u4eba\u7c7b\u548c\u52a8\u7269\u9aa8\u9abc\u5065\u5eb7\u7684\u6162\u6027\u75be\u75c5\u3002\u5b83\u901a\u5e38\u662f\u591a\u56e0\u7d20\u5f15\u8d77\u7684\uff0c\u5305\u62ec\u8870\u8001\u3001\u6fc0\u7d20\u6c34\u5e73\u4e0b\u964d\u3001\u8425\u517b\u4e0d\u5747\u8861\u3001\u6162\u6027\u75be\u75c5\u548c\u957f\u671f\u670d\u836f\u7b49\u3002\u5176\u4e3b\u8981\u7279\u5f81\u662f\u9aa8\u9abc\u5931\u53bb\u5bc6\u5ea6\u548c\u8d28\u91cf\uff0c\u5bfc\u81f4\u9aa8\u9abc\u53d8\u5f97\u8106\u5f31\u3001\u5bb9\u6613\u9aa8\u6298\u7684\u72b6\u51b5\u3002\u5371\u5bb3\u4e3b\u8981\u5305\u62ec\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>
\u589e\u52a0\u9aa8\u6298\u98ce\u9669\uff0c\u751a\u81f3\u53ef\u80fd\u5bfc\u81f4\u957f\u671f\u6b8b\u75be\u548c\u751f\u6d3b\u80fd\u529b\u4e0b\u964d\u3002<\/p><\/li>
\u589e\u52a0\u7ecf\u6d4e\u8d1f\u62c5\uff0c\u53ef\u80fd\u9700\u8981\u624b\u672f\u3001\u5eb7\u590d\u8bad\u7ec3\u3001\u966a\u62a4\u548c\u8425\u517b\u7b49\u8bf8\u591a\u5f00\u652f\u3002<\/p><\/li>
\u884c\u52a8\u4e0d\u4fbf\uff0c\u4e25\u91cd\u7684\u53ef\u80fd\u9700\u8981\u5367\u5e8a\uff0c\u5eb7\u590d\u8fc7\u7a0b\u53ef\u80fd\u9700\u8981\u957f\u65f6\u95f4\uff0c\u4e25\u91cd\u5f71\u54cd\u751f\u6d3b\u8d28\u91cf\u548c\u5fc3\u7406\u5065\u5eb7\u3002<\/p><\/li><\/ul>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t \u867d\u7136\u9aa8\u8d28\u758f\u677e\u75c7\u662f\u4e00\u79cd\u5e38\u89c1\u7684\u4eba\u755c\u75be\u75c5\uff0c\u4e14\u5371\u5bb3\u8f83\u5927\uff0c\u4f46\u662f\u5176\u7279\u70b9\u662f\u53d1\u75c5\u7f13\u6162\u7684\u6162\u6027\u75c5\u3002\u56e0\u6b64\uff0c\u65e9\u671f\u8bca\u65ad\u548c\u9884\u9632\u662f\u6cbb\u7597\u9aa8\u8d28\u758f\u677e\u75c7\u7684\u5173\u952e\u3002<\/strong><\/p> \u200b\u8981\u5bf9\u4ed8\u9aa8\u8d28\u758f\u677e\u75c7\uff0c\u751f\u7269\u6807\u8bb0\u7269 (Biomarkers) \u662f\u73b0\u884c\u6d41\u884c\u7684\u8bca\u65ad\u65b9\u6cd5\u3002<\/p> \u751f\u7269\u6807\u8bb0\u7269\u662f\u6307\u5728\u4f53\u5185\u53ef\u4ee5\u6307\u793a\u751f\u7269\u4f53\u751f\u7406\u72b6\u6001\u3001\u75c5\u7406\u72b6\u6001\u6216\u836f\u7269\u53cd\u5e94\u7684\u5206\u5b50\u3002\u901a\u8fc7\u751f\u7269\u4f53\u5185\u7684\u751f\u7269\u6837\u672c (\u4f8b\u5982\u8840\u6db2\u3001\u5c3f\u6db2\u3001\u553e\u6db2\u3001\u7ec4\u7ec7\u7b49) \u8fdb\u884c\u68c0\u6d4b\uff0c\u53ef\u4ee5\u5e2e\u52a9\u533b\u751f\u66f4\u65e9\u5730\u53d1\u73b0\u75be\u75c5\u3001\u76d1\u6d4b\u75be\u75c5\u7684\u8fdb\u5c55\u3001\u8bc4\u4f30\u6cbb\u7597\u6548\u679c\u3002<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t \u96cc\u6fc0\u7d20\u6c34\u5e73\u4f4e\u4e0b\u88ab\u8ba4\u4e3a\u662f\u5bfc\u81f4\u9aa8\u8d28\u758f\u677e\u75c7\u7684\u4e3b\u8981\u539f\u56e0\u3002\u5375\u5de2\u6458\u9664 (ovariectomy\uff0c\u7b80\u79f0OVX) \u5c0f\u9f20\u662f\u4e00\u79cd\u8f83\u6210\u719f\u7684\u52a8\u7269\u6a21\u578b\uff0c\u901a\u8fc7\u53cc\u4fa7\u5375\u5de2\u6458\u9664\u672f\uff0c\u53ef\u4ee5\u6210\u529f\u5efa\u7acb\u6a21\u62df\u96cc\u6fc0\u7d20\u7f3a\u4e4f\u800c\u5bfc\u81f4\u7684\u9aa8\u8d28\u758f\u677e\u52a8\u7269\u6a21\u578b\u3002<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t \u672c\u7814\u7a76\u65e8\u5728\u5e94\u7528\u5e72\u8840\u6591\u6280\u672f\u5bf9 OVX \u6a21\u578b\u5c0f\u9f20\u548c\u6b63\u5e38\u5bf9\u7167\u5c0f\u9f20\u8fdb\u884c\u65b9\u4fbf\u3001\u5fae\u91cf\u5730\u91c7\u6837\uff0c\u7814\u7a76\u4e24\u8005\u5e72\u8840\u6591\u6837\u672c\u4e2d\u4ee3\u8c22\u4ea7\u7269\u7684\u5dee\u5f02\uff0c\u5bf9\u6f5c\u5728\u8868\u5f81\u5c0f\u9f20\u9aa8\u8d28\u758f\u677e\u75c7\u7684\u751f\u7269\u6807\u8bb0\u7269\u8fdb\u884c\u7b5b\u67e5\u3002<\/p>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t OVX \u6a21\u578b\u5c0f\u9f20\u548c\u6b63\u5e38\u5bf9\u7167\u5c0f\u9f20\u7684\u5e72\u8840\u6591\u6837\u672c\u00a0<\/p><\/section><\/section><\/section> \u6c28\u57fa\u9178\u7c7b\u3001\u8102\u80aa\u9178\u7c7b\u548c\u80c6\u6c41\u9178\u7c7b\u4ee3\u8c22\u4ea7\u7269<\/p><\/section><\/section><\/section> Ahlstrom AutoCollectTM\u00a0<\/sup><\/p><\/section><\/section><\/section> \u5ba4\u6e29<\/p><\/section><\/section><\/section> \u76f4\u63a5\u63d0\u53d6<\/p><\/section><\/section><\/section> \u6db2\u76f8\u8272\u8c31-\u8d28\u8c31 (LC-MS)<\/p><\/section><\/section><\/section>\u751f\u7269\u6807\u8bb0\u7269
\n\n\n\u662f\u76d1\u6d4b\u9aa8\u8d28\u758f\u677e\u75c7\u7684\u6700\u4f73\u65b9\u6cd5<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\tDBS \u5e72\u8840\u6591\u5e94\u7528\u6848\u4f8b:
\n\n\u5c0f\u9f20\u9aa8\u8d28\u758f\u677e\u75c7
\n\n\u751f\u7269\u6807\u8bb0\u7269\u7684\u7814\u7a76<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\u6837\u672c<\/strong><\/h5><\/section><\/section><\/section><\/section><\/section>
\u68c0\u6d4b\u76ee\u6807<\/strong><\/h5><\/section><\/section><\/section><\/section><\/section>
\u5361\u7247<\/strong><\/h5><\/section><\/section><\/section><\/section><\/section>
\u6837\u672c\u8fd0\u8f93\u6761\u4ef6<\/strong><\/h5><\/section><\/section><\/section><\/section><\/section>
\u63d0\u53d6\u65b9\u6cd5<\/strong><\/h5><\/section><\/section><\/section><\/section><\/section>
\u68c0\u6d4b\u65b9\u6cd5<\/strong><\/h5><\/section><\/section><\/section><\/section><\/section>
\u7ed3\u679c<\/strong><\/h5><\/section><\/section>\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t