{"id":1530,"date":"2018-09-18T17:00:49","date_gmt":"2018-09-18T09:00:49","guid":{"rendered":"http:\/\/www.nikyang.com\/?p=1530"},"modified":"2021-08-25T12:19:48","modified_gmt":"2021-08-25T04:19:48","slug":"the-iodine-nutritional-status-of-pregnant-women-is-clear-at-all","status":"publish","type":"post","link":"https:\/\/www.nikyang.com\/bio-sample-prep\/the-iodine-nutritional-status-of-pregnant-women-is-clear-at-all\/","title":{"rendered":"\u3010\u5b9e\u65f6\u8ffd\u8e2a\u3011\u5168\u51ed\u5e72\u8840\u6591\u6280\u672f \u5b55\u5987\u7898\u8425\u517b\u72b6\u51b5\u4e00\u76ee\u4e86\u7136"},"content":{"rendered":"<p><strong>\u7898\u4f5c\u4e3a\u4e00\u79cd\u81ea\u7136\u754c\u5e7f\u6cdb\u5b58\u5728\u7684\u8425\u517b\u5143\u7d20\uff0c<\/strong>\u5bf9\u4e8e\u4eba\u7684\u8eab\u4f53\u5065\u5eb7\u6709\u7740\u4e0d\u5bb9\u5ffd\u89c6\u7684\u5f71\u54cd\uff0c\u56e0\u6b64\u4e0d\u5c11\u5b55\u5987\u90fd\u683c\u5916\u5173\u6ce8\u7898\u6444\u5165\u91cf\u7684\u52a8\u6001\u53d8\u5316\u3002\u4e0d\u79d1\u5b66\u6444\u5165\u5bb9\u6613\u5f15\u8d77\u7532\u72b6\u817a\u75be\u75c5\uff0c\u751a\u81f3\u589e\u52a0\u6d41\u4ea7\u7b49\u98ce\u9669\uff0c\u5bf9\u8179\u4e2d\u5a74\u513f\u7684\u53d1\u80b2\u4f1a\u4ea7\u751f\u6d88\u6781\u7684\u5f71\u54cd\u3002<\/p>\n<div class=\"qb_sc_image_container\"><img class=\"alignnone wp-image-1531 size-full\" src=\"\/wp-content\/uploads\/2018\/09\/sszz-1.jpg\" alt=\"\" width=\"332\" height=\"168\" srcset=\"\/wp-content\/uploads\/2018\/09\/sszz-1.jpg 332w, \/wp-content\/uploads\/2018\/09\/sszz-1-300x152.jpg 300w\" sizes=\"(max-width: 332px) 100vw, 332px\" \/><\/div>\n<p>\u5e94\u7528 DMS \u6280\u672f\u539f\u7406\uff0c\u5e72\u8840\u6591\u91c7\u6837 (DBS) \u6280\u672f<strong>\u53ea\u9700\u91c7\u96c6\u6307\u5c16\u8840\u53ca\u4e13\u7528\u5361\u7eb8\u6536\u96c6\uff0c<\/strong>\u4fbf\u53ef\u76d1\u6d4b\u7898\u8425\u517b\u72b6\u51b5\u3002<\/p>\n<div class=\"qb_sc_image_container\"><img class=\"alignnone wp-image-1532 size-full\" src=\"\/wp-content\/uploads\/2018\/09\/sszz-2.jpg\" alt=\"\" width=\"500\" height=\"305\" srcset=\"\/wp-content\/uploads\/2018\/09\/sszz-2.jpg 500w, \/wp-content\/uploads\/2018\/09\/sszz-2-300x183.jpg 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/div>\n<section>\n<section>\n<section>\n<section>\u5b9e\u9a8c\u8bc1\u660e\uff0c\u6548\u679c\u53ef\u9760<\/section>\n<\/section>\n<\/section>\n<\/section>\n<p>\u7814\u7a76\u8005Sara Stinca, Maria Andersson 2017\u5e74\u5728JCEM (The Journal of Clinical Endocrinology &amp; Metabolism ) \u4e0a\u53d1\u8868\u4e86\u6587\u732e[1]\uff0c<strong>\u8bc1\u660e\u7528 DBS \u91c7\u6837\u65b9\u6cd5\u53ef\u68c0\u6d4b\u5b55\u5987\u7684\u7532\u72b6\u817a\u7403\u86cb\u767d (Tg)\uff0c<\/strong>\u800c\u7532\u72b6\u817a\u7403\u86cb\u767d\u53ef\u80fd\u662f\u5b55\u671f\u5b55\u5987\u7684\u7898\u8425\u517b\u72b6\u51b5\u7684\u654f\u611f\u751f\u7269\u6807\u5fd7\u7269\uff0c\u56e0\u6b64\u53ef\u76d1\u6d4b\u5b55\u671f\u7898\u8425\u517b\u72b6\u51b5\u3002<\/p>\n<section><strong>\u6587\u732e\u91cc\u63d0\u5230\u8be5\u7814\u7a76\u76ee\u7684\uff1a<\/strong><\/p>\n<section>1) \u5efa\u7acb\u5e72\u8840\u6591\u91c7\u6837 (DBS) \u6280\u672f\u68c0\u6d4b Tg \u65f6\u7684\u7898\u5145\u8db3\u5b55\u5987\u53c2\u8003\u8303\u56f4\uff1b2) \u5bf9\u4e00\u4e9b\u5217\u4e0d\u540c\u7898\u6444\u5165\u91cf\u7684\u5b55\u5987\u8fdb\u884c\u53c2\u8003\u8303\u56f4\u6d4b\u8bd5\uff1b3) \u786e\u5b9a\u662f\u5426\u6709\u8054\u5408 Tg \u6297\u4f53 (Ab) \u6d4b\u91cf\u4eba\u7fa4\u7898\u8425\u517b\u72b6\u51b5\u7684\u5fc5\u8981\u3002\u672c\u9879\u6807\u51c6\u6a2a\u65ad\u9762\u7814\u7a76\uff0c\u7eb3\u5165\u4e86\u6765\u81ea 11 \u4e2a\u56fd\u5bb6\u7684 3870 \u4f4d\u5b55\u5987\uff0c\u7898\u6444\u5165\u91cf\u4ece\u7f3a\u4e4f\u5230\u8db3\u591f\u591a\u3002\u4e3a\u4e86\u5b9a\u4e49 DBS-Tg \u53c2\u8003\u8303\u56f4\uff0c\u7814\u7a76\u8005\u7eb3\u5165\u4e86\u7532\u72b6\u817a\u673a\u80fd\u6b63\u5e38\u7684\u3001TgAb \u9634\u6027\u5b55\u5987 (n=599)\uff0c\u6765\u81ea 3 \u4e2a\u7898\u6444\u5165\u91cf\u5145\u8db3\u7684\u56fd\u5bb6\u3002\u4e3b\u8981\u6d4b\u91cf\u503c\u4e3a\u5c3f\u7898\u6d53\u5ea6 (UIC) \u548cDBS TSH\u3001\u603bT4\u3001Tg\u548cTgAb\u3002\u6570\u636e\u663e\u793a\uff0c\u5728\u53c2\u8003\u5b55\u5987\u4eba\u7fa4\u4e2d\uff0c\u4e2d\u4f4d\u6570DBS-Tg (95%CI) \u503c\u4e3a9.2 (8.7-9.8) \u03bcg\/L\uff1b\u4e0d\u540c\u598a\u5a20\u671f\u4e4b\u95f4\u6ca1\u6709\u5dee\u5f02\uff1b\u53c2\u8003\u8303\u56f4\u4e3a0.3-43.5 \u03bcg\/L\u3002\u7ed3\u679c\u8868\u660e\uff0cDBS-Tg\u662f\u5b55\u5987\u5b55\u671f\u7898\u8425\u517b\u72b6\u51b5\u7684\u654f\u611f\u751f\u7269\u6807\u5fd7\u7269\u3002\u6839\u636e\u6d4b\u91cf\uff0c\u4e2d\u4f4d\u6570 DBS-Tg \u224810 \u03bcg\/L \u65f6\uff0c\u4e14\u4f4e\u4e8e 3% \u7684\u503c \u226544 \u03bcg\/L\uff0c\u8868\u660e\u4eba\u7fa4\u7898\u8425\u517b\u5145\u8db3\uff0c\u800c\u8bc4\u4f30\u4eba\u7fa4\u7898\u8425\u517b\u72b6\u51b5\u65f6\uff0c\u6ca1\u6709\u5fc5\u8981\u53bb\u6d4b\u91cf Tg \u6297\u4f53 (Ab)\u3002<\/section>\n<\/section>\n<p>\u5982\u6709\u5174\u8da3\u8bd5\u7528DMS \/ DBS \u8fd9\u4e2a\u65b0\u6280\u672f\uff0c\u6b22\u8fce\u4e0e\u6211\u4eec\u8054\u7cfb\u3002<\/p>\n<section>\n<section><strong>\u53c2\u8003\u6587\u732e\uff1a<\/strong>[1] Sara Stinca, Maria Andersson, et al.\u00a0 Dried Blood Spot Thyroglobulin as a Biomarker of Iodine Status in Pregnant Women. J Clin Endocrinol Metab(2017) 102(1): 23-32. DOI: https:\/\/doi.org\/10.1210\/jc.2016-2829\u4e2d\u6587\u62a5\u9053\u53c2\u8003:http:\/www.medsci.cn\/article\/show_article.do?id=8b1c8024302<\/section>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>\u7898\u4f5c\u4e3a\u4e00\u79cd\u81ea\u7136\u754c\u5e7f\u6cdb\u5b58\u5728\u7684\u8425\u517b\u5143\u7d20\uff0c\u5bf9\u4e8e\u4eba\u7684\u8eab\u4f53\u5065\u5eb7\u6709\u7740\u4e0d\u5bb9\u5ffd\u89c6\u7684\u5f71\u54cd\uff0c\u56e0\u6b64\u4e0d\u5c11\u5b55\u5987\u90fd\u683c\u5916\u5173\u6ce8\u7898\u6444\u5165\u91cf\u7684\u52a8\u6001\u53d8\u5316\u3002\u4e0d\u79d1\u5b66\u6444\u5165\u5bb9\u6613\u5f15\u8d77\u7532\u72b6\u817a\u75be\u75c5\uff0c\u751a\u81f3\u589e\u52a0\u6d41\u4ea7\u7b49\u98ce\u9669\uff0c\u5bf9\u8179\u4e2d\u5a74\u513f\u7684\u53d1\u80b2\u4f1a\u4ea7\u751f\u6d88\u6781\u7684\u5f71\u54cd\u3002 \u5e94\u7528 DMS \u6280\u672f\u539f\u7406\uff0c\u5e72\u8840\u6591\u91c7\u6837 (DBS) \u6280\u672f\u53ea\u9700\u91c7\u96c6\u6307\u5c16\u8840\u53ca\u4e13\u7528\u5361\u7eb8\u6536\u96c6\uff0c\u4fbf\u53ef\u76d1\u6d4b\u7898\u8425\u517b\u72b6\u51b5\u3002 \u5b9e\u9a8c\u8bc1\u660e\uff0c\u6548\u679c\u53ef\u9760 \u7814\u7a76\u8005Sara Stinca, Maria Andersson 2017\u5e74\u5728JCEM (The Journal of Clinical Endocrinology &amp; Metabolism ) \u4e0a\u53d1\u8868\u4e86\u6587\u732e[1]\uff0c\u8bc1\u660e\u7528 DBS \u91c7\u6837\u65b9\u6cd5\u53ef\u68c0\u6d4b\u5b55\u5987\u7684\u7532\u72b6\u817a\u7403\u86cb\u767d (Tg)\uff0c\u800c\u7532\u72b6\u817a\u7403\u86cb\u767d\u53ef\u80fd\u662f\u5b55\u671f\u5b55\u5987\u7684\u7898\u8425\u517b\u72b6\u51b5\u7684\u654f\u611f\u751f\u7269\u6807\u5fd7\u7269\uff0c\u56e0\u6b64\u53ef\u76d1\u6d4b\u5b55\u671f\u7898\u8425\u517b\u72b6\u51b5\u3002 \u6587\u732e\u91cc\u63d0\u5230\u8be5\u7814\u7a76\u76ee\u7684\uff1a 1) \u5efa\u7acb\u5e72\u8840\u6591\u91c7\u6837 (DBS) \u6280\u672f\u68c0\u6d4b Tg \u65f6\u7684\u7898\u5145\u8db3\u5b55\u5987\u53c2\u8003\u8303\u56f4\uff1b2) \u5bf9\u4e00\u4e9b\u5217\u4e0d\u540c\u7898\u6444\u5165\u91cf\u7684\u5b55\u5987\u8fdb\u884c\u53c2\u8003\u8303\u56f4\u6d4b\u8bd5\uff1b3) \u786e\u5b9a\u662f\u5426\u6709\u8054\u5408 Tg \u6297\u4f53 (Ab) \u6d4b\u91cf\u4eba\u7fa4\u7898\u8425\u517b\u72b6\u51b5\u7684\u5fc5\u8981\u3002\u672c\u9879\u6807\u51c6\u6a2a\u65ad\u9762\u7814\u7a76\uff0c\u7eb3\u5165\u4e86\u6765\u81ea 11 \u4e2a\u56fd\u5bb6\u7684 3870 \u4f4d\u5b55\u5987\uff0c\u7898\u6444\u5165\u91cf\u4ece\u7f3a\u4e4f\u5230\u8db3\u591f\u591a\u3002\u4e3a\u4e86\u5b9a\u4e49 DBS-Tg \u53c2\u8003\u8303\u56f4\uff0c\u7814\u7a76\u8005\u7eb3\u5165\u4e86\u7532\u72b6\u817a\u673a\u80fd\u6b63\u5e38\u7684\u3001TgAb \u9634\u6027\u5b55\u5987 (n=599)\uff0c\u6765\u81ea 3 \u4e2a\u7898\u6444\u5165\u91cf\u5145\u8db3\u7684\u56fd\u5bb6\u3002\u4e3b\u8981\u6d4b\u91cf\u503c\u4e3a\u5c3f\u7898\u6d53\u5ea6 (UIC) \u548cDBS TSH\u3001\u603bT4\u3001Tg\u548cTgAb\u3002\u6570\u636e\u663e\u793a\uff0c\u5728\u53c2\u8003\u5b55\u5987\u4eba\u7fa4\u4e2d\uff0c\u4e2d\u4f4d\u6570DBS-Tg (95%CI) \u503c\u4e3a9.2 (8.7-9.8) \u03bcg\/L\uff1b\u4e0d\u540c\u598a\u5a20\u671f\u4e4b\u95f4\u6ca1\u6709\u5dee\u5f02\uff1b\u53c2\u8003\u8303\u56f4\u4e3a0.3-43.5 \u03bcg\/L\u3002\u7ed3\u679c\u8868\u660e\uff0cDBS-Tg\u662f\u5b55\u5987\u5b55\u671f\u7898\u8425\u517b\u72b6\u51b5\u7684\u654f\u611f\u751f\u7269\u6807\u5fd7\u7269\u3002\u6839\u636e\u6d4b\u91cf\uff0c\u4e2d\u4f4d\u6570 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1576,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[186],"tags":[97,131],"_links":{"self":[{"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/posts\/1530"}],"collection":[{"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/comments?post=1530"}],"version-history":[{"count":6,"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/posts\/1530\/revisions"}],"predecessor-version":[{"id":1577,"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/posts\/1530\/revisions\/1577"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/media\/1576"}],"wp:attachment":[{"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/media?parent=1530"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/categories?post=1530"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nikyang.com\/wp-json\/wp\/v2\/tags?post=1530"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}